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Targets Recommended: Chloride channel

1

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T7638 NPPB

Chloride channel Membrane transporter/Ion channel
NPPB 是外向整流氯化物通道阻断剂,IC50 为 80 nM。

化合物

NPPB
Cat.No: T7638
Synonym:
Target: Chloride channel
Cat. No. Product Name Species Expression System
TMPJ-00875 NPPB Protein, Human, Recombinant (His)

NPPB,γ-Brain Natriuretic Peptide,Gamma-Brain Natriu...

Human E. coli
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.
TMPJ-00874 NT-proBNP Protein, Human, Recombinant (His & Flag)

γ-brain natriuretic peptide,Gamma-brain natriuretic peptide,...

Human E. coli
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such ...
TMPH-03250 NPR3 Protein, Rat, Recombinant (His & SUMO)

Rat E. coli
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system wi...
TMPJ-00878 NPR3 Protein, Human, Recombinant (hFc)

ANPRC,ANPR-C,C5orf23,NPR-C,NPRC,NPR3,ANP-C

Human HEK293 Cells
Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for N...
TMPH-00985 NPR3 Protein, Human, Recombinant (His)

Human E. coli
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-...

重组蛋白

NPPB Protein, Human, Recombinant (His)
Cat.No: TMPJ-00875
Species: Human
Expression System: E. coli
NT-proBNP Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00874
Species: Human
Expression System: E. coli
NPR3 Protein, Rat, Recombinant (His & SUMO)
Cat.No: TMPH-03250
Species: Rat
Expression System: E. coli
NPR3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00878
Species: Human
Expression System: HEK293 Cells
NPR3 Protein, Human, Recombinant (His)
Cat.No: TMPH-00985
Species: Human
Expression System: E. coli
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