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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7638 |
NPPB
|
Chloride channel | Membrane transporter/Ion channel |
NPPB 是外向整流氯化物通道阻断剂,IC50 为 80 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00875 |
NPPB Protein, Human, Recombinant (His)
NPPB,γ-Brain Natriuretic Peptide,Gamma-Brain Natriu... |
Human | E. coli |
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3. | |||
TMPJ-00874 |
NT-proBNP Protein, Human, Recombinant (His & Flag)
γ-brain natriuretic peptide,Gamma-brain natriuretic peptide,... |
Human | E. coli |
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such ... | |||
TMPH-03250 |
NPR3 Protein, Rat, Recombinant (His & SUMO)
|
Rat | E. coli |
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system wi... | |||
TMPJ-00878 |
NPR3 Protein, Human, Recombinant (hFc)
ANPRC,ANPR-C,C5orf23,NPR-C,NPRC,NPR3,ANP-C |
Human | HEK293 Cells |
Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for N... | |||
TMPH-00985 |
NPR3 Protein, Human, Recombinant (His)
|
Human | E. coli |
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-... |