Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12219 |
NHE3-IN-1
|
Sodium Channel | Membrane transporter/Ion channel |
NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。 | |||
T61480 |
NHE3-IN-3
|
||
NHE3-IN-3 (Compound 1) is a potent inhibitor of the isoform 3 of the Na+/H+ exchanger (NHE3). It exhibits pIC50 values of 6.2 and 6.6 against human and rat NHE3, respectively. Furthermore, NHE3-IN-3 showcases exceptional oral bioavailability of 98% in Sprague–Dawley rats [1]. | |||
T60652 |
NHE3-IN-2
|
||
NHE3-IN-2 是Na+/H+交换体 3(NHE3)的抑制剂 。 |