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Cat. No. Product Name Target Signaling Pathways
T18616 NH2-C2-NH-Boc

PROTAC Linker 22,N-叔丁氧羰基-1,2-乙二胺

Others; PROTAC Linker Others; PROTAC
NH2-C2-NH-Boc (PROTAC Linker 22) 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
T16520 Ph-Bis(C1-N-(C2-NH-Boc)2)

Others Others
Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker employed in the synthesis of PROTACs[1].
T39524 Thalidomide-NH-PEG2-C2-NH-Boc

Thalidomide-NH-PEG2-C2-NH-Boc

Thalidomide-NH-PEG2-C2-NH-Boc, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon-targeting Thalidomide ligand with a PEG linker for the synthesis of dBRD9 (compound 6). This selective BRD9 probe PROTAC degrader is utilized in researching BAF complex biology.
T16296 NH-bis(C2-PEG2-NH-Boc)

Others Others
NH-bis(C2-PEG2-NH-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16299 NH-bis(PEG2-C2-Boc)

Others Others
NH-bis(PEG2-C2-Boc) is an alkyl/ether-based linker, utilized for the synthesis of PROTACs[1].
T14816 Bromoacetamido-C2-PEG2-NH-Boc

Others Others
Bromoacetamido-C2-PEG2-NH-Boc is a polyethylene glycol (PEG)-based linker with a bromoacetamido functional group and a tert-butoxycarbonyl (Boc) protecting group. It serves as an integral component in the synthesis of proteolysis-targeting chimeras (PROTACs), which are innovative compounds used for targeted protein degradation[1].
T17745 DBCO-C2-PEG4-NH-Boc

Others Others
DBCO-C2-PEG4-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16661 NH2-PEG5-C2-NH-Boc

PROTAC Linker 17

Others Others
NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based compound utilized as a linker in the synthesis of PROTACs[1].
T14736 Boc-NH-PEG2-C2-NHS ester

Others Others
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-derived PROTAC linker employed for the synthesis of PROTACs[1].
T16659 Boc-NH-PEG2-C2-NH2

PROTAC Linker 13

Others Others
Boc-NH-PEG2-C2-NH2 (PROTAC Linker 13) is a PEG-based linker utilized for the synthesis of PROTACs. This chemical compound plays a crucial role in connecting the targeted protein and the E3 ubiquitin ligase for selective protein degradation[1].
T14163 Ald-Ph-amido-C2-PEG3-NH-Boc

Others Others
Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T18484 NH2-C2-amido-C2-Boc

Others Others
NH2-C2-amido-C2-Boc is an alkyl/ether-based PROTAC linker employed in the synthesis of various PROTACs, including the PROTAC CDK2/9 Degrader-1[1]. NH2-C5-NH-Boc can also serve as a suitable precursor for the synthesis of these PROTACs.
T16311 NH2-PEG2-C2-Boc

Others Others
NH2-PEG2-C2-Boc is a polyethylene glycol (PEG)-based PROTAC linker utilized for synthesizing PROTACs[1]. It serves as a non-cleavable 2-unit PEG linker for antibody-drug conjugates (ADCs) in their synthesis[2].
T18623 Boc-NH-PEG2-C2-amido-C4-acid

PROTAC Linker 30

Others Others
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T20098 NH2-PEG3-C2-Boc

Amino-PEG3-t-butyl ester

Amino-PEG3-t-butyl ester is a PEG derivative containing an amino group with the t-butyl protected carboxyl group. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
T17906 Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc

E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20

Others Others
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a novel synthesized conjugate compound functioning as an E3 ligase ligand-linker in PROTAC technology. This compound incorporates a Pomalidomide-derived cereblon ligand, which binds selectively to the E3 ligase cereblon, and a 2-unit PEG linker, which provides stability and flexibility to the conjugate.

化合物

NH2-C2-NH-Boc
Cat.No: T18616
Synonym: PROTAC Linker 22,N-叔丁氧羰基-1,2-乙二胺
Target: Others, PROTAC Linker
Ph-Bis(C1-N-(C2-NH-Boc)2)
Cat.No: T16520
Synonym:
Target: Others
Thalidomide-NH-PEG2-C2-NH-Boc
Cat.No: T39524
Synonym: Thalidomide-NH-PEG2-C2-NH-Boc
Target:
NH-bis(C2-PEG2-NH-Boc)
Cat.No: T16296
Synonym:
Target: Others
NH-bis(PEG2-C2-Boc)
Cat.No: T16299
Synonym:
Target: Others
Bromoacetamido-C2-PEG2-NH-Boc
Cat.No: T14816
Synonym:
Target: Others
DBCO-C2-PEG4-NH-Boc
Cat.No: T17745
Synonym:
Target: Others
NH2-PEG5-C2-NH-Boc
Cat.No: T16661
Synonym: PROTAC Linker 17
Target: Others
Boc-NH-PEG2-C2-NHS ester
Cat.No: T14736
Synonym:
Target: Others
Boc-NH-PEG2-C2-NH2
Cat.No: T16659
Synonym: PROTAC Linker 13
Target: Others
Ald-Ph-amido-C2-PEG3-NH-Boc
Cat.No: T14163
Synonym:
Target: Others
NH2-C2-amido-C2-Boc
Cat.No: T18484
Synonym:
Target: Others
NH2-PEG2-C2-Boc
Cat.No: T16311
Synonym:
Target: Others
Boc-NH-PEG2-C2-amido-C4-acid
Cat.No: T18623
Synonym: PROTAC Linker 30
Target: Others
NH2-PEG3-C2-Boc
Cat.No: T20098
Synonym: Amino-PEG3-t-butyl ester
Target:
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc
Cat.No: T17906
Synonym: E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20
Target: Others
TargetMol Loading
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