Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35717 |
N-desmethyl Rosiglitazone
|
Others | Others |
N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone. |