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Cat. No. Product Name Target Signaling Pathways
T7091 N-Formyl-Met-Leu-Phe

fMLP,N-Formyl-MLF

TNF Apoptosis
N-Formyl-Met-Leu-Phe (N-Formyl-MLF) 是一种趋化肽和N-甲酰基肽受体的特异性配体,可抑制TNF-alpha 的分泌。
TP1168 N-Formyl-Met-Leu-Phe-Lys

fMLFK

Others Others
N-Formyl-Met-Leu-Phe-Lys (fMLFK) 是一种多肽,是选择性FPR1激动剂,作用于 FPR1(IC50:3.5 nM),FPR2(IC50:6.7 nM) 和 FPR2-D2817.32G(IC50:0.88 nM) 。
TP1672L N-Formyl-Met-Ala-Ser TFA(17351-32-5 free base)

Others Others
N-Formyl-Met-Ala-Ser TFA(17351-32-5 free base) 是一种肽,与中性粒细胞上的甲酰肽受体结合。N-Formyl-Met-Ala-Ser 肽 (fMet-Ala-Ser) 与中性粒细胞上的甲酰肽受体结合。含有 N-甲酰甲硫氨酸的肽包括有效和已知的成员 N-甲酰-Met-Leu-Phe(FMLP 或 fMet-Leu-Phe)通过受体依赖性机制刺激人中性粒细胞。
TP1672 N-Formyl-Met-Ala-Ser

N-Formyl-Met-Ala-Ser is a peptide, binds to formyl peptide receptors on neutrophils.N-Formyl-Met-Ala-Ser Peptide (fMet-Ala-Ser) binds to formyl peptide receptors on neutrophils. N-Formylmethionine-containing peptides including the most potent and known me
T36355 Sydowinin B

Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 μg/ml, respectively).2Sydowinin B inhibits superoxide generation in, and elastase release from, isolated human neutrophils induced by cytochalasin B and N-Formyl-Met-Leu-Phe with IC50values of 21.2 and 12.62 μM, respectively.3
T83798 8-bromo NAD+ sodium

8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+

8-bromo NAD+ 作为循环ADP-核糖(cADPR)抑制剂8-bromo cADPR的前药形式,通过CD38转化为8-bromo-cADPR。在1 mM浓度下,8-bromo NAD+ 阻止由N-formyl-Met-Leu-Phe (fMLP) 在分离的小鼠骨髓衍生的中性粒细胞内引起的细胞内钙水平增加和趋化作用。同时,在100 µM浓度下使用,减少了小鼠原代小胶质细胞中LPS诱导的亚硝酸盐产生以及TNF-α和IL-2的分泌。

化合物

N-Formyl-Met-Leu-Phe
Cat.No: T7091
Synonym: fMLP,N-Formyl-MLF
Target: TNF
N-Formyl-Met-Leu-Phe-Lys
Cat.No: TP1168
Synonym: fMLFK
Target: Others
N-Formyl-Met-Ala-Ser TFA(17351-32-5 free base)
Cat.No: TP1672L
Synonym:
Target: Others
N-Formyl-Met-Ala-Ser
Cat.No: TP1672
Synonym:
Target:
Sydowinin B
Cat.No: T36355
Synonym:
Target:
8-bromo NAD+ sodium
Cat.No: T83798
Synonym: 8-bromo Nicotinamide adenine dinucleotide,N(8-bromo-A)D+
Target:
TargetMol Loading
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