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Cat. No.	Product Name	Target	Signaling Pathways
T2176	2,3-Butanedione 2-Monoxime Diacetyl monoxime,2,3-Butanedione-2-monoxime	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) 是一种肌球蛋白 ATP 酶(myosin ATPase) 抑制剂。它诱导肌质网 Ca2+释放，能够有效抑制骨骼肌和心肌收缩。
T7144	BTS N-Tosylbenzylamine,N-苄基-对甲苯磺酸胺,N-Benzyl-p-toluenesulfonamide	ATPase; Myosin	Cytoskeletal Signaling; Membrane transporter/Ion channel
	BTS (N-Tosylbenzylamine) 是一种选择性骨骼肌肌球蛋白 II 亚片段 1 (S1) ATPase 活性抑制剂，可特异性抑制骨骼肌快速纤维的收缩。它对肌动蛋白和 Ca2+刺激的肌球蛋白 S1 ATPase 的 IC50值约为 5 µM。
T7134	Mavacamten MYK-461,SAR439152	Myosin	Cytoskeletal Signaling
	Mavacamten (MYK-461) 是一种可口服的心肌肌球蛋白 ATP 酶抑制剂，在牛心脏和人心脏中的IC50值分别为 490和711 nM。
T12503	(+)-Blebbistatin	Others	Others
	(+)-Blebbistatin 是 (–)-Blebbistatin 的非活性对映异构体。 (–)-Blebbistatin 是一种选择性肌球蛋白 II ATPase 抑制剂。
T72060	Myosin V-IN-1	Myosin	Cytoskeletal Signaling
	Myosin V-IN-1是一种有效且具有选择性的 Myosin V 抑制剂，Ki 值为 6 μM。Myosin V-IN-1 抑制肌动蛋白 V 发生作用，通过选择性抑制肌动球蛋白复合物释放 ADP 来减缓肌动蛋白激活的肌球蛋白 V ATP 酶。
T67951	JB061	Myosin	Cytoskeletal Signaling
	JB061是一种非肌肉肌球蛋白II抑制剂，针对心肌肌球蛋白、骨骼肌肌球蛋白和平滑肌肌球蛋白II的IC50分别为4.4 μM、9.1 μM和>100 μM。其对ATP酶活性的抑制作用较弱（IC50>200 μM）。此外，JB061对COS-7细胞显示出细胞毒性，IC50值为39 μM。
T23992	Diazobenzenesulfonic acid Diazobenzenesulphonate,diazobenzene sulfonic acid,DASA,Diazobenzene sulfonate,Diazobenzenesulfonate
	Diazobenzenesulfonic acid is a whiter or reddish crystalline acid derivative of sulfanilic acid. It is a desensitizer (inhibitor) of allosteric effect for myosin ATPase 13.
T36335	(S)-nitro-Blebbistatin
	(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, it blocks apoptosis-related bleb formation, directed cell migration, and cytokinesis in vertebrate cells. H...
T36400	para-amino-Blebbistatin
	para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases that rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM).2,3,4 Through these effects, it blocks ap...