Cat. No. | Product Name | Target | Signaling Pathways |
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T62305 |
MtTMPK-IN-2
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MtTMPK-IN-2 (compound 15)为一高效MtbTMPK抑制剂,IC50值达1.1 μM。该化合物对MtbH37Rv表现出抑制活性(MIC = 12.5 μM),同时对人成纤维细胞MRC-5显示出一定细胞毒性(EC50= 6.1 μM)。MtTMPK-IN-2适用于结核病研究。 | |||
T61780 |
MtTMPK-IN-4
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MtTMPK-IN-4 (compound 2), a para-piperidine, is a highly potent inhibitor of thymidylate kinase (MtTMPK) in Mycobacterium tuberculosis, exhibiting an IC50 value of 6.1 μM. Additionally, it possesses remarkable inhibitory activity against tyrosinase. Furthermore, MtTMPK-IN-4 exhibits potent antibacterial properties [1] [2]. |