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Cat. No.	Product Name	Target	Signaling Pathways
T12111L	MS31 trihydrochloride (2366264-12-0 free base) MS31 trihydrochloride	Epigenetic Reader Domain	Chromatin/Epigenetic
	MS31 trihydrochloride (2366264-12-0 free base) 是一种有效的、高亲和力和选择性的片段样甲基赖氨酸阅读蛋白 spindlin 1 (SPIN1) 抑制剂。
T12111	MS31	Others	Others
	MS31 is a potent and highly affinity inhibitor of spindlin 1 (SPIN1).
T62729	MS31 trihydrochloride
	MS31 trihydrochloride 是一种选择性的、高亲和性的、片段样的甲基赖氨酸读写蛋白 spindlin 1 (SPIN1) 抑制剂。MS31 trihydrochloride 有效破坏 SPIN1 与 H3K4me3 蛋白互相作用 (IC50: 77 nM，AlphaLISA；243 nM，FP)，选择性结合 SPIN1 的 Tudor 结构域 II (Kd: 91 nM)。MS31 trihydrochloride 对含三甲基赖氨酸肽与 SPIN1 的结合具有有效抑制作用，对非肿瘤性细胞没有毒性。
T35520	Aflatoxin G1-13C17 Aflatoxin G1-13C17
	Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase...
T35519	Aflatoxin B2-13C17 Aflatoxin B2-13C17
	Aflatoxin B2-13C17(AFB2-13C17) is intended for use as an internal standard for the quantification of AFB2by GC- or LC-MS. AFB2is a mycotoxin that has been found inA. terricola.1It induces hepatic autophagy and apoptosis in broiler chickens when administered at doses of 0.2, 0.4, and 0.8 mg/kg.2AFB2(0.5 and 1 mg/animal) also induces parenchymal cell hyperplasia in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Alimen...
T35521	Aflatoxin G2-13C17 Aflatoxin G2-13C17
	Aflatoxin G2-13C17is intended for use as an internal standard for the quantification of aflatoxin G2by GC- or LC-MS. Aflatoxin G2is a mycotoxin that has been found inAspergillus.1It is lethal to ducklings (LD50= 2.83 mg/kg) but is non-toxic to rats when administered at a dose of 200 mg/kg.2 1.Bennett, J.W., and Klich, M.MycotoxinsClin. Microbiol. Rev.16(3)497-516(2003) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins a...
T35683	2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...