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Search Results for " mpn "

3

抑制剂 & 化合物

2

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40565	5MPN
	5MPN is a novel compound that functions as a highly potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4). This compound demonstrates oral activity and serves as a first-in-class inhibitor. Through competitive inhibition of the F6P binding site, 5MPN effectively hinders the functionality of PFKFB4, with a Ki value of 8.6 μM. Importantly, it exhibits no inhibitory effects on PFK-1 or PFKFB3. By specifically targeting the sugar metabolism of tumors, 5MPN...
T80667	2-Methyl-1-Pyrroline	Others	Others
	2-Methyl-1-Pyrroline (2-MPN）是一种光化学染料的中间体，可诱导 (R）-2-MP的形成。
T79581	JAK2-IN-9	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2-IN-9（Compound A8）是一款选择性JAK2抑制剂（IC50：5 nM），能够抑制JAK2、STAT3和STAT5的磷酸化，并显示出代谢稳定性。此外，JAK2-IN-9能够诱导细胞凋亡（apoptosis），适用于骨髓增生性肿瘤（MPN）的研究。

化合物

Cat.No: T40565

2-Methyl-1-Pyrroline

Cat.No: T80667

Target: Others

Cat.No: T79581

Target: JAK

Cat. No.	Product Name	Target	Signaling Pathways
T82786	Campneoside II
	Campneoside II, 分离自毛泡桐，展现出显著的抗补体活性。
TN7032	4'-O-Methylpyridoxine 4-methoxymethylpyridoxine,Ginkgotoxin	Antioxidant	oxidation-reduction
	4'-O-Methylpyridoxine（MPN）是从银杏叶中发现的维生素类化合物，具有抗氧化活性和细胞毒性。

天然产物

Cat.No: T82786

4'-O-Methylpyridoxine

Cat.No: TN7032

Synonym: 4-methoxymethylpyridoxine,Ginkgotoxin

Target: Antioxidant

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02117	Marapsin Protein, Human, Recombinant (His) UNQ1884/PRO4327,protease, serine 27,CAPH2,MPN	Human	HEK293 Cells
	The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most stro...

重组蛋白

Marapsin Protein, Human, Recombinant (His)

Cat.No: TMPY-02117

Species: Human

Expression System: HEK293 Cells

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