Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4677 |
MMAD
Monomethylauristatin D,Demethyldolastatin 10,单甲基澳瑞他汀 D,Monomethyl Dolastatin 10 |
Microtubule Associated | Cytoskeletal Signaling |
MMAD (Demethyldolastatin 10) 是一种有效的微管蛋白抑制剂,是抗体药物偶联物中的一种毒素有效载荷。 | |||
T18870 |
Vc-MMAD
|
Others | Others |
Vc-MMAD 由 linker (Val-Cit) 和微管抑制剂 MMAD 组成。Vc-MMAD 可用于偶联抗体。 | |||
T18311 |
Mc-MMAD
|
Others | Others |
Mc-MMAD, a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporates the protective group maleimidocaproyl (Mc) conjugated to monomethyl auristatin D (MMAD), a potent inhibitor of tubulin. | |||
T10947 |
D8-MMAD
Monomethylauristatin D D8,Demethyldolastatin 10 D8,Monomethyl Dolastatin 10 D8 |
Others | Others |
D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer. | |||
T74075 | MC-VC-PAB-MMAD | ||
MC-VC-PAB-MMAD为一种抗体-活性分子偶联物,连接了微管抑制剂MMAD与可降解的ADC linker MC-VC-PAB。 | |||
T74074 | OSu-Glu-VC-PAB-MMAD | ||
OSu-Glu-VC-PAB-MMAD是由微管抑制剂MMAD与可降解的ADC linker OSu-Glu-VC-PAB通过一种高度特异性的连接方式构成,作为抗体-活性分子偶联物(antibody-drug conjugates, ADCs)中的关键组成部分。 | |||
T5326 |
Sugammadex sodium
Org25969,Sugammadex (sodium),舒更葡糖钠 |
Others | Others |
Sugammadex sodium (Org25969) 是合成的 γ 环糊精衍生物,是一种新型的神经肌肉阻断逆转剂。 | |||
T17741 |
Cys-mcMMAD
|
Others | Others |
Cys-mcMMAD is a drug-linker conjugate for ADC. MMAD is a potent tubulin inhibitor. | |||
T5326L |
Sugammadex
Org-25969,Org25969,Org 25969,361LPM2T56 |
||
Sugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periph |