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Cat. No. Product Name Target Signaling Pathways
T70718 CR-6086

CR6086 is a novel, potent EP4 antagonist showing favourable immunomodulatory properties, striking DMARD effects in rodents, and anti-inflammatory activity targeted to immune-mediated inflammatory diseases and distinct from the general effects of cyclooxygenase inhibitors. CR6086 showed selectivity and high affinity for the human EP4 receptor (Ki = 16.6 nM) and functioned as a pure antagonist (half-maximal inhibitory concentration, 22 nM) on PGE2-stimulated cAMP production.
T70719 MLAF50

MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.

化合物

CR-6086
Cat.No: T70718
Synonym:
Target:
MLAF50
Cat.No: T70719
Synonym:
Target:
TargetMol Loading
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