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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T4399 ML239

CID-49843203

Others Others
ML239 (CID-49843203) 是乳腺癌肿瘤干细胞的选择性抑制剂(C50:1.16 μM)。
T2112 Fexinidazole

非昔硝唑,HOE 239

Others; Parasite Microbiology/Virology; Others
Fexinidazole (HOE 239) 是具有口服活性的硝基咪唑抗锥虫药物。它显示出对布鲁氏杆菌亚种和菌株的杀锥虫活性,IC50值为 0.7-3.3 μM (0.2-0.9 μg/ml)。它具有用于因感染布鲁氏菌引起的人类昏睡病的潜力。

化合物

ML239
Cat.No: T4399
Synonym: CID-49843203
Target: Others
Fexinidazole
Cat.No: T2112
Synonym: 非昔硝唑,HOE 239
Target: Others, Parasite
Cat. No. Product Name Target Signaling Pathways
T35624 Ajoene

Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Ajoene
Cat.No: T35624
Synonym:
Target:
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