Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16109 |
ML402
ZINC3671497,N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide |
Potassium Channel | Membrane transporter/Ion channel |
ML402 (ZINC3671497) 是 TREK-1 和 TREK-2 的激动剂,EC50 为 13.7 μM 和 5.9 μM。 | |||
T35700 |
FR901379
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FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection. |1. Fujie, A., Iwamoto, T., Sato, B., et al. FR131535, a novel water-soluble echinocandin-like lipopeptide: Synthesis and bi... |