Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3303 |
ML277
ML-277,CID-53347902 |
Potassium Channel | Membrane transporter/Ion channel |
ML277 (CID-53347902) 是一种有效的,选择性K(v)7.1 钾离子通道激动剂,EC50为270nM。 | |||
T38005 |
P11149
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P11149 is a competitive, BBB-penetarated weakly, orally active and selective inhibitor of AChE. P11149 exhibits an IC50 of 1.3 μM for rat BChE/AChE. P11149, a Galanthamine derivative, demonstrates central cholinergic activity, behavioral efficacy and safety. P11149 is used in the study for Alzheimer’s disease[1]. P11149 is a GAL analog that is rapidly hydrolyzed in vivo to yield the potent AChE inhibitor, 6-DMG[1].P11149 exhibits greater s.c. bioavailability than p.o. [1].Oral P11149 in mice pr... |