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Targets Recommended: HIF

1

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36953 Naphthofluorescein

Naphthafluorescein

HIF Angiogenesis; Chromatin/Epigenetic
Naphthofluorescein (Naphthafluorescein)是一种 Mint3 抑制剂,具有潜在的抗肿瘤和抗炎活性,抑制 HIF-1 和 Mint3 之间的相互作用,抑制 Mint3 依赖性 HIF-1 活性,抑制癌细胞和巨噬细胞的糖酵解活动,同时未显示出明显的体外细胞毒性和体内副作用。Naphthofluorescein 也是一种荧光 pH 敏感探针,可用于功能性切伦科夫成像。

化合物

Naphthofluorescein
Cat.No: T36953
Synonym: Naphthafluorescein
Target: HIF
Cat. No. Product Name Species Expression System
TMPJ-00722 APBA3 Protein, Human, Recombinant (His)

Neuronal Munc18-1-Interacting Protein 3,Neuron-Spec...

Human E. coli
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amylo...

重组蛋白

APBA3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00722
Species: Human
Expression System: E. coli
TargetMol Loading
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