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Search Results for " mcd "

Targets Recommended: IL Receptor

4

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T76978	Siltuximab CNTO-328	IL Receptor	Immunology/Inflammation
	Siltuximab（CNTO-328）是一种靶向 IL-6 且具有抗肿瘤活性的单克隆抗体，可用于研究巨大淋巴结增生症 (MCD) 和 COVID-19。
T40950	A3334
	A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD) and methionine-choline deficient diet (MCD).
T37405	Octanoyl Coenzyme A (sodium salt)
	Octanoyl coenzyme A (octanoyl-CoA) is a medium-chain acyl CoA and a metabolic intermediate in mitochondrial fatty acid β-oxidation. Levels of octanoyl-CoA are increased in the liver of patients with Reye's syndrome and β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH) is decreased in patients with MCADH deficiency (MCD). Octanoyl-CoA inhibits citrate synthase and glutamate dehydrogenase.
T79454	Anti-NASH agent 1	PPAR	DNA Damage/DNA Repair; Metabolism
	Anti-NASH agent 1 (compound 3d)，Elafibranor衍生物，高效PPAR-α/δ激动剂，针对非酒精性脂肪性肝炎（NASH）。以3-10 mg/kg剂量，连续4周处理，能显著改善蛋氨酸胆碱缺乏（MCD）诱导的NASH小鼠高脂血症、肝脏脂肪变性及炎症状况，展现出低肝毒性和良好肝脏保护效能。

化合物

Cat.No: T76978

Synonym: CNTO-328

Target: IL Receptor

Cat.No: T40950

Octanoyl Coenzyme A (sodium salt)

Cat.No: T37405

Anti-NASH agent 1

Cat.No: T79454

Target: PPAR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02005	Mucin-1/MUC1 Protein, Human, Recombinant (hFc) PEM,ADMCKD1,CA15-3,CD227,MCD,mucin 1, cell surface ...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42 kDa and the accession number is P15941-11.
TMPY-04340	Mucin-1/MUC1 Protein, Human, Recombinant mucin 1, cell surface associated,MUC-1/SEC,PEM,MUC1/ZD,MUC-1...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.4 kDa and the accession number is P15941-11.
TMPY-06833	Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His) MUC1/ZD,MUC-1,MUC-1/SEC,CA15-3,mucin 1, cell surface associa...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.28 kDa and the accession number is P15941-1.
TMPY-06832	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His) PEM,MUC-1,EMA,H23AG,Mucin 1,PEMT,mucin 1, cell surface assoc...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.19 kDa and the accession number is P15941-1.
TMPY-06707	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surface associa...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPY-02871	Mucin-1/MUC1 Protein, Human, Recombinant (mFc) mucin 1, cell surface associated,ADMCKD1,EMA,MCKD1,Mucin 1,M...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41 kDa and the accession number is P15941-11.
TMPJ-01364	LMCD1 Protein, Human, Recombinant (His) LMCD1,Dyxin,LIM and cysteine-rich domains protein 1	Human	E. coli
	LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critic...
TMPH-01634	MLYCD Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic ...

重组蛋白

Mucin-1/MUC1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02005

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant

Cat.No: TMPY-04340

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His)

Cat.No: TMPY-06833

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His)

Cat.No: TMPY-06832

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

Cat.No: TMPY-06707

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-02871

Species: Human

Expression System: HEK293 Cells

LMCD1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01364

Species: Human

Expression System: E. coli

MLYCD Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01634

Species: Human

Expression System: E. coli

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