Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11959 |
MBM-17S
|
Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic |
MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and apoptosis. It demonstrates antitumor activities without evident toxicity to mice. |