Cat. No. | Product Name | Target | Signaling Pathways |
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T75138 | Lipid 14 | ||
Lipid 14 是一种可电离的氨基脂质,可用于合成脂质纳米粒 (LNPs)。 | |||
T38041 |
(R)-3-hydroxy Myristic Acid
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Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria. LPS is composed of polysaccharides and lipid A, where lipid A is a phosphoglycolipid containing acyl chains composed of 10 to 16 carbons. The lipid A component of LPS is detected by Toll-like receptor 4 of mammalian leukocytes and, thus, is a key determinant in immune response. (R)-3-Hydroxymyristic Acid is a form of the 14:0 lipid myristic acid that is found in the lipid A component of some Gram-negative bacte... | |||
T74305 |
14:0 PEG2000 PE
DMPE-PEG2000 |
Others | Others |
14: 0 PEG2000 PE (DMPE-PEG2000) 是一种聚乙二醇 (PEG)-磷脂偶联物,可在制备囊泡制剂时阻止囊泡聚集,可用于制备纳米结构脂质载体。 | |||
T74319 |
14:0 DAP
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14:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) 是一种阳离子脂质,可用于药物递送。 | |||
T74320 |
14:0 EPC chloride
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14:0 EPC chloride 是一种酰基阳离子脂质,用于药物递送中的脂质体。 | |||
T38341 |
11(Z),14(Z)-Eicosadienoic Acid methyl ester
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11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid , a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5'-monophosphate dehydrogenase (Ki = 3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki = 3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance. Eicosadienoic acids are converted by desaturases, in vi... | |||
T37996 |
17-phenyl trinor Prostaglandin E2 ethyl amide
17-phenyl trinor Prostaglandin E2 ethyl amide |
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17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively). 17-phenyl trinor PGE2 causes contraction of guinea pig ileum at a concentration of 11 μM and is 4.4 times more potent than PGE2 as an antifertility agent in hamsters. Modification of the C-1 carboxyl group to an ethyl amide serves to inc... | |||
T36152 |
14S(15R)-EET
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14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid .114S(15R)-EET binds to isolated guinea pig monocytes with a Kivalue of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.2It induces dilation of precontracted isolated canine epicardial arterioles (EC50= 4 pM) and denuded porcine subepicardial arterioles (EC50= 3 pM).3Unlike 14R(15S)-EET, 14S(15R)-EET does not inhibit COX in enzyme assays or isolated platelets.4 1.Daikh, B.E., Lasker, J.M., Raucy, J.L., ... |