Cat. No. | Product Name | Target | Signaling Pathways |
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T35796 |
Lactosylceramides (bovine buttermilk)
LacCer (bovine buttermilk) |
ROS | Immunology/Inflammation |
Lactosylceramides (bovine buttermilk) (LacCer (bovine buttermilk)) 是从牛酪乳中分离出来的神经酰胺,抑制细胞增殖,可用于研究肿瘤和肝脏病变。 | |||
T36582 |
Glucocerebrosides (Gaucher's spleen)
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Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase. They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species. Glucocerebrosides are precursors in the synthesis of lactosylceramides and gangliosides. Increased levels of glucocerebrosides are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease. This pr... | |||
T36185 | Globotriaosylceramides (hydroxy) (porcine) | ||
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G... | |||
T36186 |
Globotriaosylceramides (porcine)
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Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G... |