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Search Results for " lactacystin "

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抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38034 MAO-IN-M30 dihydrochloride

M 30 dihydrochloride

Monoamine Oxidase Neuroscience
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) 是一种口服活性,可通过血脑屏障的,脑选择性不可逆 MAO-A (IC50=37 nM) 和 MAO-B (IC50=57 nM) 抑制剂。MAO-IN-M30 dihydrochloride 是有效的铁螯合剂、自由基清除剂。MAO-IN-M30 dihydrochloride 对 Dexamethasone 诱导的脑细胞凋亡具有神经保护作用。MAO-IN-M30 dihydrochloride 在 MPTP 和 lactacystin 帕金森病模型中也显示出神经恢复活性。
T24158 ICL-SIRT078

ICLSIRT078,ICL SIRT 078,ICL SIRT078,ICL-SIRT-078

ICL-SIRT078 is a highly selective inhibitor of substrate-competitive SIRT2 that acts by displaying a significant neuroprotective effect in a lactacystin-induced model of Parkinsonian neuronal cell death in the N27 cell line.

化合物

MAO-IN-M30 dihydrochloride
Cat.No: T38034
Synonym: M 30 dihydrochloride
Target: Monoamine Oxidase
ICL-SIRT078
Cat.No: T24158
Synonym: ICLSIRT078,ICL SIRT 078,ICL SIRT078,ICL-SIRT-078
Target:
Cat. No. Product Name Target Signaling Pathways
T15702 Lactacystin

Proteasome Proteases/Proteasome; Ubiquitination
Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and also inhibits the lysosomal enzyme cathepsin A.

天然产物

Lactacystin
Cat.No: T15702
Synonym:
Target: Proteasome
TargetMol Loading
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