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Search Results for " ly96 "

1

抑制剂 & 化合物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T83729	Tat-CIRP TFA Tat-Cold-inducible RNA Binding Protein
	Tat-CIRP是一种肽类抑制剂，用于抑制髓样分化2蛋白(MD-2，亦称淋巴细胞抗原96 [LY96])与寒冷诱导的RNA结合蛋白(CIRP)之间的蛋白-蛋白相互作用。它通过与MD-2结合，干扰MD-2与CIRP之间的相互作用，这一作用在共免疫沉淀实验中得到证实。在体内实验中，Tat-CIRP (10及20 mg/kg) 能够减少由中脑动脉闭塞(MCAO)引发的小鼠脑梗死体积。同样，在通过血栓引发脑梗死的恒河猴模型中，Tat-CIRP同样能减少脑梗死体积，并缩短患中风一侧手臂抓取并放下食物的时间。

化合物

Cat.No: T83729

Synonym: Tat-Cold-inducible RNA Binding Protein

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00632	MD2/LY96 Protein, Cynomolgus, Recombinant (His) ESOP-1,LY96,Lymphocyte antigen	Cynomolgus	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0.
TMPK-01242	MD2/LY96 Protein, Human, Recombinant (His) MD-2,Ly-96,ESOP-1,Lymphocyte anti...	Human	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1.
TMPY-03999	MD2/LY96 Protein, Mouse, Recombinant (hFc) lymphocyte antigen 96,ESOP-1,MD2,MD-2	Mouse	HEK293 Cells
	LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances the TLR4-dependent activa...
TMPY-02904	TLR4 Protein, Human, Recombinant (His) TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284	Human	Baculovirus Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed...
TMPJ-00527	SP-D Protein, Human, Recombinant (His) Lung Surfactant Protein D,SFTP4,COLEC7,SFTPD,PSP-D,SP-D,Pulm...	Human	HEK293 Cells
	Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. ...

重组蛋白

MD2/LY96 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00632

Species: Cynomolgus

Expression System: E. coli

MD2/LY96 Protein, Human, Recombinant (His)

Cat.No: TMPK-01242

Species: Human

Expression System: E. coli

MD2/LY96 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03999

Species: Mouse

Expression System: HEK293 Cells

TLR4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02904

Species: Human

Expression System: Baculovirus Insect Cells

SP-D Protein, Human, Recombinant (His)

Cat.No: TMPJ-00527

Species: Human

Expression System: HEK293 Cells

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