T11880
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LSD1-IN-5
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Histone Demethylase |
Chromatin/Epigenetic |
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LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-5 is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. |
T72388
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CBB1007 hydrochloride
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CBB1007 hydrochloride,一种可逆的、选择性的高效组蛋白去甲基化酶LSD1的底物竞争性抑制剂,其对hLSD1的IC50值为5.27 uM。 |
T72244
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CBB1007 trihydrochloride
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CBB1007三盐酸盐是 LSD1选择性抑制剂,IC50值为5.27uM。 |
T36668
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Geranylgeranoic Acid
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Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not primary mouse hepatocytes, when used at concentrations ranging from 1 to 20 μM. GGA (10 μM) induces apoptosis in Huh7 cellsvialoss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32).2It also... |