Cat. No. | Product Name | Target | Signaling Pathways |
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T21654 |
1-Oleoyl lysophosphatidic acid sodium
1-Oleoyl lysophosphatidic acid sodium salt |
LPA Receptor | GPCR/G Protein |
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt 是 LPA1 和 LPA2 的内源性激动剂,可通过诱导 DNA 合成促进有丝分裂,参与正常和病理性情绪反应,如焦虑和抑郁。 | |||
T77789 |
Oleoyl-L-alpha-lysophosphatidic acid sodium salt
LPA sodium salt |
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Oleoyl-L-alpha-lysophosphatidic acid sodium salt为必需的细胞膜生物合成代谢物,可通过与G蛋白偶联受体(GPCR)(即LPA受体)相互作用来介导信号传导,是LPA1和LPA2受体的内源性激动剂。 | |||
T36452 |
1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
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1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differe... |