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Search Results for " ln1 "

Targets Recommended: IκB/IKK

4

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0306	MLN120B	IκB/IKK	NF-κB
	MLN120B 是一种ATP 竞争性的、有效的、具有口服活性的IKKβ抑制剂，IC50=60 nM。它在体内外抑制多发性骨髓瘤细胞生长，也可用于研究类风湿关节炎。
T64293	SLN124
	SLN124 是一种 GalNac-siRNA，靶向跨膜丝氨酸蛋白酶 6 (Tmprss6)，由与 TMPRSS6-siRNA 结合的三聚体 GalNAc 配体组成。SLN124 具有潜力用做 siRNA 剂，恢复铁调素表达并使 β-地贫中铁稳态正常化。
T75928	des-Gln14-Ghrelin TFA
	des-Gln14-Ghrelin TFA为生长激素促分泌受体的第二个内源性配体。该化合物能在CHO-GHSR62细胞中诱导[Ca2+]I的提升，其EC50值为2.4 nM。
TP2032	des-Gln14-Ghrelin des-Gln14-Ghrelin (rat)
	An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH release in vivo.

化合物

Cat.No: TQ0306

Target: IκB/IKK

Cat.No: T64293

des-Gln14-Ghrelin TFA

Cat.No: T75928

des-Gln14-Ghrelin

Cat.No: TP2032

Synonym: des-Gln14-Ghrelin (rat)

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03109	PHYH Protein, Human, Recombinant PHYH1,RD,PAHX,LN1,phytanoyl-CoA 2...	Human	E. coli
	PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentos...
TMPY-00819	HAPLN1 Protein, Human, Recombinant (His) CRTL1,hyaluronan and proteoglycan link protein ...	Human	HEK293 Cells
	Hyaluronan (HA) is a high MW glycosaminoglycan significantly involved in the formation and stability of extracellular matrix via its association with specific HA-binding proteins. HAPLN1, also known as CRTL1 (Cartilage Link Protein 1, CLP) and link protein, is a member of the HA-binding protein (hyaladherins) family, and contains a common structural domain of about 100 amino acids that is termed a Link module with two α-helices and two antiparallel β-sheets. HAPLN1/CRTL1 stabilizes the interacti...
TMPH-01540	Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not ...
TMPH-01710	Mucolipin-1/MCOLN1 Protein, Human, Recombinant (His)	Human	E. coli
	Mucolipin-1/MCOLN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 66.5 kDa and the accession number is Q9GZU1.
TMPH-01280	EGLN1 Protein, Human, Recombinant (His & Myc) HPH-2,EGLN1,PHD2,SM-20,HIF-prolyl hydroxyl...	Human	E. coli
	Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquiti...
TMPY-01826	Relaxin 1/RLN1 Protein, Human, Recombinant (His) RLXH1,H1RLX,relaxin 1,bA1	Human	HEK293 Cells
	Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductive hormone 8 years ago, relaxin has been implicated in a number of pregnancy-related functions involving extracellular matrix (ECM) turnover and collagen degradation. It is now becoming evident that relaxin's ability to reduce matrix synthesis and increase ECM degradation has impo...

重组蛋白

PHYH Protein, Human, Recombinant

Cat.No: TMPY-03109

Species: Human

Expression System: E. coli

HAPLN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00819

Species: Human

Expression System: HEK293 Cells

Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01540

Species: Human

Expression System: E. coli

Mucolipin-1/MCOLN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01710

Species: Human

Expression System: E. coli

EGLN1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01280

Species: Human

Expression System: E. coli

Relaxin 1/RLN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01826

Species: Human

Expression System: HEK293 Cells

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