Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12475 |
PIM447
LGH447 |
Others | Others |
PIM447 is a potent, orally available, and selective inhibitor of pan-PIM kinase(PIM1, PIM2, and PIM3 with Ki values of 6, 18, and 9 pM , respectively). | |||
T12473 |
PIM-447 dihydrochloride
LGH447 dihydrochloride |
Others | Others |
PIM-447 dihydrochloride is an orally available and selective inhibitor of pan-PIM kinase(Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively). | |||
T13425 |
(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-LGH447 dihydrochloride |
CDK | Cell Cycle/Checkpoint |
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3). |