Cat. No. | Product Name | Target | Signaling Pathways |
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T71520 |
LEQ-506
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LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth. | |||
T11838 |
LEQ506
NVP-LEQ506 |
Smo | Stem Cells |
LEQ506 是一种 Smo 抑制剂,对 hSmo 和 mSmo 的 IC50 分别为 2 nM 和 4 nM。 | |||
T24400 |
LEQ-506 HCl (1204975-42-7 free base)
LEQ-506,LEQ-506 dihychloride,NPVLEQ 506,LEQ506,LEQ-506 HCl,LEQ 506 |
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LEQ506 is an orally bioavailable small-molecule Smoothened antagonist. It also has a potential antineoplastic activity. | |||
T71518 | Zidovudine diphosphate | ||
Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming. |