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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T4103	(L)-Sodium lactate L-乳酸钠,Sodium L-Lactate	Others	Others
	(L)-Sodium lactate (Sodium L-Lactate) 是由乳酸脱氢酶从丙酮酸中产生的。它在无氧糖酵解过程中或增殖活跃的细胞中产生。它在人和动物的血液和肌肉液中少量存在。剧烈运动后，肌肉和血液中的乳酸浓度会增加。它也存在于肝脏、肾脏、胸腺、人羊水以及其他器官和体液中。
T40923	Calcium lactate Lactic acid calcium,Hemicalcium L-lactate,Lactate calcium,乳酸钙,Conclyte calcium	Others	Others
	Calcium lactate (Conclyte calcium) 被饮料工业用作强化果汁的钙源。Calcium lactate 促进豆芽生长和植酸降解。
T32809	L-Lactate ion L-Lactate,Lactate ion, L-
	L-Lactate ion is the conjugate base of lactic acid.
T21151	AT-9283 L-lactate AT-9283,AT 9283,AT9283
	AT-9283 L-lactate is an inhibitor of aurora kinase.
T76116	L-Lactate dehydrogenase
	L-Lactate dehydrogenase (L-乳酸脱氢酶) 是一种氧化还原酶。L-Lactate dehydrogenase 在体内催化 NADH 将丙酮酸还原为 L-乳酸。
T41001	L-Lactic acid-13C3 L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3
	L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.
T36498	CAY10762 CAY10762
	CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50= 34.1 nM).1It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 μM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain. 1.Castelli, R., Scalvini, L., Vacondio, F., et al.Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteinesJ. Med. Chem.63(...
T71305	Clofibric Acid-d4
	Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal...

化合物

(L)-Sodium lactate

Cat.No: T4103

Synonym: L-乳酸钠,Sodium L-Lactate

Target: Others

Calcium lactate

Cat.No: T40923

Synonym: Lactic acid calcium,Hemicalcium L-lactate,Lactate calcium,乳酸钙,Conclyte calcium

Target: Others

L-Lactate ion

Cat.No: T32809

Synonym: L-Lactate,Lactate ion, L-

Target:

AT-9283 L-lactate

Cat.No: T21151

Synonym: AT-9283,AT 9283,AT9283

Target:

L-Lactate dehydrogenase

Synonym: L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3

Target:

CAY10762

Cat.No: T36498

Synonym: CAY10762

Cat. No.	Product Name	Target	Signaling Pathways
T5220	D-(-)-Lactic acid sodium Sodium D-lactate,D-乳酸钠	Others; Endogenous Metabolite	Metabolism; Others
	D-(-)-Lactic acid sodium (Sodium D-lactate) 是一种有机酸。它是一种手性分子，由 L-乳酸和 D-乳酸两种光学异构体组成，其中 L-异构体在生物体中最常见。D-(-)-Lactic acid sodium 也是一种微生物代谢产物。
T5290	(S)-2-Hydroxy-3-phenylpropanoic acid L-(−)-3-Phenyllactic acid,L-3-苯乳酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) 是苯丙氨酸的代谢产物。苯丙酮尿症患者体液中苯丙氨酸的水平升高。
TN1013	Cucurbitacin D	Apoptosis	Apoptosis
	Cucurbitacin D 是一种从 Ecballium elaterium （L.）分离出来的三萜类化合物，具有抗癌抗肿瘤活性，抑制转移性 PrC 中的葡萄糖摄取和乳酸产生，诱导独立于 ERK1/2 激活的炎症小体激活。 Cucurbitacin D 是巨噬细胞中的一种新的炎症小体激活剂，通过调节 JAK/STAT3、PI3K/Akt/mTOR 和 MAPK 信号通路抑制 HepG2 细胞增殖并诱导细胞凋亡，可用于研究宫颈癌、白血病和前列腺癌。