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Cat. No. | Product Name | Target | Signaling Pathways |
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T81977 | Kobusine derivative-1 | ||
Kobusine derivative-1,一种Kobusine衍生物,展现出了对癌细胞显著的抗增殖活性。 | |||
T72411 | Kobusine derivative-2 | ||
Kobusine derivative-2,一种kobusine衍生物,对癌细胞显示出抗增殖活性,并能诱导MDA-MB-231细胞在亚G1期阻滞,表现出抗癌活性。 | |||
T32409 |
Kobusine
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Kobusine is an aconite alkaloid of the C20-diterpenoid type. |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN1834 |
Kobusin
去甲槟郎碱,自旋七叶素 |
Others; NOS; NF-κB | Immunology/Inflammation; NF-κB; Others |
Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-express... |