Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11752 |
Keap1-Nrf2-IN-1
Keap1–Nrf2-IN-1 |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
Keap1–Nrf2 IN-1 activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models. Keap1–Nrf2 IN-1 is a Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 ( | |||
T64218 | Keap1-Nrf2-IN-1 TFA | ||
Keap1-Nrf2-IN-1 TFA (compound35) 是一种 Keap1-Nrf2 蛋白-蛋白相互作用抑制剂 (IC50: 43 nM),可以激活 Nrf2 调节的细胞保护反应。在细胞和体内模型中。Keap1-Nrf2-IN-1 TFA 能够拮抗对乙酰氨基酚诱导的肝损伤。 |