Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12428L |
PF-06726304
|
Histone Methyltransferase | Chromatin/Epigenetic |
PF-06726304 是选择性EZH2有效抑制剂,具有强抗肿瘤生长活性。它抑制野生型和 Y641N 突变型 EZH2,Ki 分别为 0.7 和 3.0 nM。 | |||
T39889 | Antitumor agent-23 | ||
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respectively. |