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Cat. No.	Product Name	Target	Signaling Pathways
TP1895L1	KYL acetate(676657-00-4 free base)	Ephrin Receptor	Tyrosine Kinase/Adaptors
	KYL acetate(676657-00-4 free base) 是EphA4受体酪氨酸激酶抑制剂（Kd = 0.8 μM）；抑制 EphA4-EphrinA5 相互作用 (IC50 = 6.34 μM)。防止 AβO 诱导的突触损伤、树突棘丢失并防止海马 CA3-CA1 传输中 LTP 的阻断。在细胞培养基中表现出较长的半衰期（在 PC3 和 C2C12 培养基中分别为 8 和 12 小时）。它有神经保护作用。
TP1895	KYL peptide KYL
	KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
T40030	Thalidomide 4'-ether-alkylC2-amine hydrochloride halidomide-linker 6	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker，是合成的 E3 连接酶配体-linker 偶联物，可应用于 PROTAC 技术。
T0604	Desalkylterbuthylazine	Others	Others
	Desalkylterbuthylazine 用作医药中间体。
T36281	VH 032 amide-alkylC5-amine VH 032 amide-alkylC5-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 13 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36279	VH 032 amide-alkylC3-amine VH 032 amide-alkylC3-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl C3 linker and terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36276	Thalidomide 4'-oxyacetamide-alkylC8-amine Thalidomide 4'-oxyacetamide-alkylC8-amine
	Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36277	VH 032 amide-alkylC2-acid VH 032 amide-alkylC2-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36273	VH 101 phenol-alkylC4-amine VH 101 phenol-alkylC4-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T70854	Protokylol hydrochloride
	Protokylol hydrochloride is the salt form of Protokylol (free base) (Asmetil, Caytine, Palison, Ventaire), a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. It is methylenedioxyphenyl-isoproterenol.
T36278	VH 032 amide-alkylC3-acid VH 032 amide-alkylC3-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for research and development; incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules.
T36263	Pomalidomide 4'-alkylC8-acid Pomalidomide 4'-alkylC8-acid
	Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T83954	VH 032 amide-alkylC7-acid (S,R,S)-AHPC-amido-C7-acid
	VH 032 amide-alkylC7-acid 是一种用于PROTAC研究与开发的功能化Von-Hippel-Lindau蛋白配体(VHL)，结合了E3连接酶配体和具有末端羧酸的alkylC7连接物，便于与目标蛋白配体偶联。该化合物是为PROTAC研发设计的一系列功能化工具分子之一。
T74372	N-Desalkyludenafil
	N-Desalkyludenafil 是 Udenafil 的代谢物。Udenafil 是一种PDE5抑制剂，用于研究勃起功能障碍。
T40053	Boc-A 410099.1 amide-alkylC4-amine Boc-A 410099.1 amide-alkylC4-amine
	Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs, comprising of an IAP ligand and an amide-alkylC4 linker terminating in an amine group. It has the ability to form conjugates with target protein ligands.
T36274	VH 101 phenol-alkylC6-amine VH 101 phenol-alkylC6-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36270	(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride VH 032 phenol-alkylC6-amine
	Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T34865	Thyminalkylamine
	Thyminalkylamine is a biochemical.
T24670	Protokylol JB-251,Protokylolum,JB 251,JB251,Protoquilol
	Protokylol is a β-adrenergic receptor agonist.
T39876	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride consists of a cereblon (CRBN) ligand for the E3 ubiquitin ligase and a linker, making it suitable for PROTACs design.
T36282	VH 032 amide-alkylC7-amine VH 032 amide-alkylC7-amine
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T35469	A 410099.1 amide-alkylC4-amine A 410099.1 amide-alkylC4-amine
	Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36283	VH 032 amide-alkylC8-acid VH 032 amide-alkylC8-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC8 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36250	Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine
	Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T83961	Thalidomide 5'-amine-alkylC6-amine
	Thalidomide 5'-amine-alkylC6-amine是用于PROTAC研究与开发的功能化cereblon配体；包含一个E3连接酶配体和一个带有末端胺基的alkylC6连接器，用于与目标蛋白配体的结合。这是一系列用于PROTAC研发的功能化工具分子之一。
T36280	VH 032 amide-alkylC4-acid VH 032 amide-alkylC4-acid
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T18306	MC-Alkyl-Hydrazine Modified MMAF	Others	Others
	MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1].

化合物

KYL acetate(676657-00-4 free base)

Cat.No: TP1895L1

Target: Ephrin Receptor

Cat.No: TP1895

Synonym: KYL

Thalidomide 4'-ether-alkylC2-amine hydrochloride

Cat.No: T40030

Synonym: halidomide-linker 6

Target: E3 Ligase Ligand-Linker Conjugate

Desalkylterbuthylazine

Cat.No: T0604

Target: Others

VH 032 amide-alkylC5-amine

Cat.No: T36281

Synonym: VH 032 amide-alkylC5-amine

VH 032 amide-alkylC3-amine

Cat.No: T36279

Synonym: VH 032 amide-alkylC3-amine

Thalidomide 4'-oxyacetamide-alkylC8-amine

Cat.No: T36276

Synonym: Thalidomide 4'-oxyacetamide-alkylC8-amine

VH 032 amide-alkylC2-acid

Cat.No: T36277

Synonym: VH 032 amide-alkylC2-acid

VH 101 phenol-alkylC4-amine

Cat.No: T36273

Synonym: VH 101 phenol-alkylC4-amine

Protokylol hydrochloride

Cat.No: T70854

VH 032 amide-alkylC3-acid

Cat.No: T36278

Synonym: VH 032 amide-alkylC3-acid

Pomalidomide 4'-alkylC8-acid

Cat.No: T36263

Synonym: Pomalidomide 4'-alkylC8-acid

VH 032 amide-alkylC7-acid

Cat.No: T83954

Synonym: (S,R,S)-AHPC-amido-C7-acid

N-Desalkyludenafil

Cat.No: T74372

Boc-A 410099.1 amide-alkylC4-amine

Cat.No: T40053

Synonym: Boc-A 410099.1 amide-alkylC4-amine

VH 101 phenol-alkylC6-amine

Cat.No: T36274

Synonym: VH 101 phenol-alkylC6-amine

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride

Cat.No: T36270

Synonym: VH 032 phenol-alkylC6-amine

Thyminalkylamine

Cat.No: T34865

Cat.No: T24670

Synonym: JB-251,Protokylolum,JB 251,JB251,Protoquilol

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Cat.No: T39876

Synonym: Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

VH 032 amide-alkylC7-amine

Cat.No: T36282

Synonym: VH 032 amide-alkylC7-amine

A 410099.1 amide-alkylC4-amine

Cat.No: T35469

Synonym: A 410099.1 amide-alkylC4-amine

VH 032 amide-alkylC8-acid

Cat.No: T36283

Synonym: VH 032 amide-alkylC8-acid

Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine

Cat.No: T36250

Synonym: Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine

Thalidomide 5'-amine-alkylC6-amine

Cat.No: T83961

VH 032 amide-alkylC4-acid

Cat.No: T36280

Synonym: VH 032 amide-alkylC4-acid

MC-Alkyl-Hydrazine Modified MMAF

Cat.No: T18306

Target: Others

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