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4

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T70786	ML252
	ML252是一种钾离子通道(potassium channel)的选择性抑制剂，主要针对KCNQ2 (Kv7.2，IC50=69 nM)。同时，ML252对细胞色素Cytochrome P450也有抑制作用，其IC50值分别为CYP1A2为6.1 nM、CYP2C9为18.9 nM、CYP3A4为3.9 nM、CYP2D6为19.9 nM。
T70788	KST012174 HCl
	KST012174 is a HIF-1α inhibitor. KST012174 involves in the HIF-1α/p300 protein−protein interaction.
T125692	Wikstrol B

T130443	(+)-Wikstromol
	(+)-Wikstromol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T130443。

化合物

Cat.No: T70786

KST012174 HCl

Cat.No: T70788

Cat.No: T125692

Cat.No: T130443

Cat. No.	Product Name	Target	Signaling Pathways
T73206	Wikstrol A
	Wikstrol A 是一种有效的抗真菌剂、抗有丝分裂剂和抗HIV-1剂。Wikstrol A 诱导稻瘟病菌菌丝体的形态变形，MMDC 值为 70.1 µM。Wikstrol 对微管聚合具有活性，IC50值为 131 µM。Wikstrol A 显示抗HIV-1活性，IC50值为 67.8 µM。

天然产物

Cat.No: T73206

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00931	Serpin A4 Protein, Human, Recombinant (His) Kallistatin,Peptidase Inhibitor 4,KST,Kallikrein In...	Human	HEK293 Cells
	Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition,...
TMPY-03453	Pleckstrin Protein, Human, Recombinant (His) pleckstrin,P47	Human	E. coli
	Pleckstrin is a protein found in platelets. Pleckstrin is the source of the name pleckstrin homology domain. Pleckstrin homology domain (PH domain) is a protein domain of approximately 12 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton. This domain can bind Phosphatidylinositol lipids within biological membranes (such as Phosphatidylinositol (3,4,5)-trisphosphate and phosphatidylinositol (4,5)-bisphosphate), and prote...

重组蛋白

Serpin A4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00931

Species: Human

Expression System: HEK293 Cells

Pleckstrin Protein, Human, Recombinant (His)

Cat.No: TMPY-03453

Species: Human

Expression System: E. coli

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