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Cat. No.	Product Name	Target	Signaling Pathways
T82703	CMKLR1 antagonist 1
	CMKLR1 antagonist 1 (compound S-26d) 为口服型趋化因子样受体 1 (CMKLR1) 拮抗剂，其在hCMKLR1感染的CHO细胞中表现出pIC50值达7.44。该化合物适用于银屑病和代谢性疾病的研究。

化合物

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Cat. No.	Product Name	Species	Expression System
TMPY-03256	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) KLR,killer cell lectin-like receptor subfamily K, m...	Human	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is P26718-1.
TMPY-00467	NKG2D/CD314 Protein, Human, Recombinant (hFc) D12S2489E,killer cell lectin-like receptor subfamily K, memb...	Human	CHO Cells
	NKG2D/CD314 Protein, Human, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is A0A024RAP8.
TMPK-00108	NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag) NKG2D,NKG2-D,CD314,KLR,D12S2489E	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag) is expressed in HEK293 mammalian cells with N-hFc-Flag tag. The predicted molecular weight is 43.4 kDa and the accession numbe...
TMPK-00107	NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled NKG2D,KLR,CD314,D12S2489E,NKG2-D	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled is expressed in HEK293 mammalian cells with N-hFc-Flag tag. The predicted molecular weight is 43.4 kDa and the a...
TMPK-00106	NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated NKG2D,NKG2-D,KLR,CD314,D12S2489E	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.0 kDa and the acc...
TMPK-00105	NKG2D/CD314 Protein, Human, Recombinant (His & Avi) NKG2-D,KLR,CD314,NKG2D,D12S2489E	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.0 kDa and the accession number ...
TMPY-06827	NKG2D/CD314 Protein, Human, Recombinant (mFc) killer cell lectin-like receptor subfamily K, member 1,NKG2-...	Human	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Human, Recombinant (mFc) is expressed in Baculovirus insect cells with mFc tag. The predicted molecular weight is 41.83 kDa and the accession number is P26718-1.
TMPJ-00097	NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) member 1,NK cell receptor D,NKG2-D-activating NK receptor,ki...	Cynomolgus	HEK293 Cells
	NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P61252.
TMPJ-00122	NKG2D/CD314 Protein, Mouse, Recombinant (His) KLR,NKG2-D type II integral membrane protein,CD314,...	Mouse	HEK293 Cells
	NKG2D/CD314 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is O54709.
TMPY-06210	KLRC2 Protein, Human, Recombinant (hFc) CD159c,NKG2-C,NKG2C	Human	HEK293 Cells
	KLRC2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.4 kDa and the accession number is P26717-1.
TMPY-06896	KLRB1 Protein, Human, Recombinant (hFc) NKR-P1,CD161,CLEC5B,hNKR-P1A,NKRP1A,NKR-P1A,NKR	Human	HEK293 Cells
	KLRB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.14 kDa and the accession number is Q12918.
TMPJ-00120	NKp80/KLRF1 Protein, Human, Recombinant (His) Lectin-like receptor F1,C-type lectin domain family 5 member...	Human	HEK293 Cells
	Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function i...
TMPH-01591	KLRG2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	KLRG2 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPK-00750	KLRG1 Protein, Mouse, Recombinant (hFc) 2F1,MAFA,MGC13600,CLEC15A,CLEC15AMAFA-LIKE,KLRG1,MA...	Mouse	HEK293 Cells
	KLRG1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 42.3 kDa and the accession number is O88713.
TMPY-03623	NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc) killer cell lectin like receptor F1,KLRF1	Cynomolgus	HEK293 Cells
	NKp80, also known as KLRF1, is an activating homodimeric C-type lectin-like receptor that is expressed on nearly all-natural killer cells and stimulates their cytotoxicity and cytokine release. NKp80 stimulates cytotoxicity upon engagement of its genetically linked ligand: myeloid-specific CTLR activation-induced C-type lectin (AICL). NKp80, but not NKp80 mutated at tyrosine 7 (NKp80/Y7F), is tyrosine phosphorylated. Accordingly, NKp80/Y7F, but not NKp80/Y3F or NKp80/Y37F, failed to induce cytot...
TMPY-04765	PKLR Protein, Human, Recombinant (His) PKRL,PKR,RPK,PKL,PK1,pyruvate kinase, liver and RBC	Human	E. coli
	Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pathway and the most common cause of hereditary nonspherocytic hemolytic anemia. Over 250 PKLR-gene mutations have been described, including missense/nonsense, splicing and regulatory mutations, small insertions, small and gross deletions, causing PKD and hemolytic anemia of variabl...
TMPK-01140	KLRG1 Protein, Human, Recombinant (hFc) MAFAL,2F1,CLEC15A,KLRG1,MGC13600,MAFA,CLEC15AMAFA-L...	Human	HEK293 Cells
	KLRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is Q96E93-1.
TMPY-06285	KLRC2 Protein, Human, Recombinant (His) CD159c,NKG2C,NKG2-C	Human	HEK293 Cells
	KLRC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.12 kDa and the accession number is P26717-1.
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His) Chemerin chemokine-like receptor 2,Gpr1,Chemokine-like recep...	Rat	E. coli
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway.
TMPY-02414	Klrb1a Protein, Mouse, Recombinant (His) Nkrp1a,NKRP12,Nkrp1-a,ly-55A,killer cell lectin-like recepto...	Mouse	HEK293 Cells
	Klrb1a Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is P27811.
TMPY-02381	NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc) Nkrp1f,MGC130066,MGC130065,Nkrp1-f,killer cell lectin-like r...	Mouse	HEK293 Cells
	NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q8VD98.
TMPH-01082	CMKLR1 Protein, Human, Recombinant (His) CMKLR1,G-protein coupled receptor ChemR23,G-protein...	Human	E. coli
	CMKLR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is Q99788.
TMPK-00116	NKp80/KLRF1 Protein, Human, Recombinant (hFc) NKp80,KLRF1,Lectin-like receptor F1,CLEC5C,ML	Human	HEK293 Cells
	NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release.

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