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Cat. No. | Product Name | Target | Signaling Pathways |
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T38789 |
BMS-984923
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BMS-984923, a highly potent silent allosteric modulator (SAM) of mGluR5, demonstrates exceptional binding affinity (K i = 0.6 nM). Additionally, this compound possesses favorable oral bioavailability and blood-brain barrier (BBB) penetration. BMS-984923 effectively inhibits the interaction between PrPC and mGluR5, preventing pathological Aβo signaling, while leaving physiological glutamate signaling unaffected. | |||
T74185 | (S,S)-BMS-984923 | ||
(S,S)-BMS-984923,BMS-984923的(S,S)-对映体,相较于其它对映体展现了较低的活性。(S,S)-BMS-984923对mGluR5受体的EC50值超过1μM,标明其在这一受体上的活性较弱。BMS-984923本身为一种高效的mGluR5沉默变构调节剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00972 |
FGFR2 Protein, Human, Recombinant (His & hFc)
K-SAM,TK14,BBDS,fibroblast growth... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPY-00423 |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
BFR-1,KGFR,TK25,JWS,ECT1,K-SA... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17. | |||
TMPK-00398 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Fibroblast growth factor receptor 2,CD332,FGFR2 β (IIIb) Dom... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPK-00847 |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 β (IIIb),KGFR,BEK,CD332,K-<... |
Mouse | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2. | |||
TMPK-00397 |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
K-sam,CD332,KGFR,Keratin... |
Human | HEK293 Cells |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.2 kDa and the accession number is P21802-1. | |||
TMPK-00475 |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
K-sam,KSAM,KGFR... |
Cynomolgus | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and the accession number is A0A2K5TL84-1. | |||
TMPK-00400 |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Fibroblast growth factor receptor 2,KGFR,FGFR-2, |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3. | |||
TMPK-00399 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Keratinocyte growth factor receptor,K-... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPY-00351 |
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
fibroblast growth factor receptor 2,TK14,FGFR2 Prot... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is P21802-21. | |||
TMPK-00401 |
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD... |
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. | |||
TMPY-04273 |
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TK25,ECT1,JWS,fibroblast growth factor receptor 2,C... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3. | |||
TMPY-04390 |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
CFD1,ECT1,K-SAM,BEK,KGFR... |
Human | Baculovirus Insect Cells |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.7 kDa and the accession number is P21802-1. | |||
TMPY-06321 |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
ECT1,CEK3,JWS,TK14,K-SAM... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.88 kDa and the accession number is NP_075259.4. | |||
TMPY-01228 |
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
TK14,CEK3,BEK,BBDS,CD332,TK |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-377, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41 kDa and the accession number is P21802-1. | |||
TMPK-00396 |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
BFR-1,FGF R2a,TK25,TK14,BEK,BBDS,... |
Human | HEK293 Cells |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42.5 kDa and the accession number is P21802-1. |