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Cat. No.	Product Name	Target	Signaling Pathways
T79581	JAK2-IN-9	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2-IN-9（Compound A8）是一款选择性JAK2抑制剂（IC50：5 nM），能够抑制JAK2、STAT3和STAT5的磷酸化，并显示出代谢稳定性。此外，JAK2-IN-9能够诱导细胞凋亡（apoptosis），适用于骨髓增生性肿瘤（MPN）的研究。
T63146	JAK2/TYK2-IN-1
	JAK2/TYK2-IN-2 是一种有效的、选择性的 TYK2 (IC50: 9 nM) 和 JAK2 (IC50: 157 nM) 抑制剂，具有抗炎作用。
T70897	Zotiraciclib HCl
	Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, w...