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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2057 |
BVT 2733
|
Dehydrogenase | Metabolism |
BVT 2733 是具有口服活性的、强效的、非甾体类11β-HSD1选择性抑制剂。它对小鼠 11β-HSD1 酶的作用 (IC50:96 nM) 比对人 11β-HSD1 酶 (IC50:3341 nM) 的作用强。它对关节炎和肥胖相关疾病具有潜在的研究价值。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN4050 |
Fargesone A
|
NOS | Immunology/Inflammation |
Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1. | |||
TN3869 | Dimeric coniferyl acetate | Others | Others |
Dimeric coniferyl acetate has anti-inflammary activity, it shows strong NO inhibition with IC50 values of 27.1 uM in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. It exhibits significant inhibitory effects on the nitric oxide pro |