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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T1584 Terbutaline Sulfate

Terbutaline hemisulfate,硫酸叔丁宁按,硫酸特布他林

Antibacterial; Adrenergic Receptor; Antibiotic GPCR/G Protein; Microbiology/Virology; Neuroscience
Terbutaline Sulfate (Terbutaline hemisulfate) 是一种具有口服活性的 β2-肾上腺素能受体激动剂,是班布特罗的活性代谢物。它可研究哮喘。
T37889 BHBM

BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1 In vivo, BHBM (1.2 mg/kg per day) increases survival in a mouse model of C. neoformans infection. |1. Haranahalli, K., Lazzarini, C., Sun, Y., et al. SAR studies on aromatic acylhydrazone-based inhibitors of fungal...
T83757 RG33 TFA

RG33是一种33个氨基酸的合成肽,与apolipoprotein A1 (ApoA1)的C-末端域中两个Y类螺旋的209-219和220-241氨基酸相对应。它能溶解含有1,2-dimyristoyl-sn-glycero-3-PC (DMPC)的多层囊泡(MLVs),形成重组HDL。与脂质结合的RG33在J774巨噬细胞中诱导胆固醇外流。RG33 (12 mg/kg)可降低胰岛素抵抗性小鼠的血糖水平。

化合物

Terbutaline Sulfate
Cat.No: T1584
Synonym: Terbutaline hemisulfate,硫酸叔丁宁按,硫酸特布他林
Target: Antibacterial, Adrenergic Receptor, Antibiotic
BHBM
Cat.No: T37889
Synonym:
Target:
RG33 TFA
Cat.No: T83757
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T36776 Terpendole C

Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 μM in rat liver microsomes). It also inhibits ACAT in J774 macrophages (IC50 = 0.46 μM) without affecting cell growth.

天然产物

Terpendole C
Cat.No: T36776
Synonym:
Target:
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