Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15586 | Intoplicine | Topoisomerase | DNA Damage/DNA Repair |
Intoplicine is an inhibitor of DNA topoisomerase I and II. | |||
T38731 |
Intoplicine dimesylate
RP 60475 dimesylate |
||
Intoplicine (RP 60475) dimesylate is a DNA topoisomerase I and II inhibitor belonging to the 7H-benzo[e]pyrido[4,3-b]indole series. It exhibits a strong affinity for DNA (K A = 2 x 10^5 /M), resulting in increased linear DNA length. |