Cat. No. | Product Name | Target | Signaling Pathways |
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T6203L |
Saxagliptin hydrochloride
BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118 |
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Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose conce | |||
T70373 |
AS2575959
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AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion. | |||
TP1566 |
GIP (1-30) amide (Human) (TFA)
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GIP (1-30) amide (Human) TFA is a glucose-dependent insulinotropic polypeptide fragment. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. | |||
TP2017 |
GIP (1-39)
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Endogenous truncated form of the incretin hormone GIP. More potent at stimulating glucose-dependent insulin secretion from rat pancreatic β-cells than GIP. | |||
T82332 |
Gastric Inhibitory Polypeptide (6-30) amide (human)
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Gastric Inhibitory Polypeptide (6-30) amide (human) 为一种肠促胰岛素激素,主要应用于糖尿病研究领域。 | |||
T75757 |
GIP, human TFA
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GIP, human TFA 是一种42个氨基酸构成的肽类激素,促进葡萄糖依赖性胰岛素释放,同时轻度抑制胃酸分泌。该激素由肠K细胞释放,响应营养摄入。 | |||
T76041 |
GIP (1-30) amide,human acetate
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GIP (1-30) amide, human acetate 为葡萄糖依赖性促胰岛素多肽(GIP)的片段,作为一种肠降血糖素激素,它能在10^-9至10^-6M的剂量范围内,依赖剂量地促进胰岛素的分泌,并有效减缓餐后血糖波动。 | |||
T83694 |
Gastric Inhibitory Peptide (1-42) (porcine) TFA
GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42) |
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胃抑制肽(GIP) (1-42)是一种内源性的42氨基酸肽类肠促素激素,能诱导胰岛素分泌。该激素在肠道神经内分泌K细胞和颌下腺中表达,并在餐后释放到循环中。GIP (1-42)抑制由组胺、五肽和胰岛素引起的胃酸和胃蛋白酶分泌,增加葡萄糖诱导的胰岛素释放,并在大鼠中刺激胃排空。 | |||
T83696 |
Gastric Inhibitory Peptide 1 (3-42) (human) TFA
Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42) |
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胃抑制肽1(GIP-1) (3-42)是肠促胰岛素激素GIP的一个肽段,同时也是GIP受体的拮抗剂。它通过血清二肽基肽酶4(DDP-4)从GIP中形成。GIP-1 (3-42) (100 nM)在减少BRIN-BD11胰腺细胞的胰岛素分泌方面起作用。在以25 nmol/kg剂量给药的ob/ob糖尿病小鼠模型中,它能增加血浆葡萄糖水平并降低血浆胰岛素水平。 | |||
T82317 |
GIP, rat
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GIP, rat 是一种由十二指肠和空肠 K 细胞在食物摄入后分泌的具有生物活性的肽,由 42 个氨基酸组成。作为肠促胰岛素激素肽家族的一员,GIP 与另一激素 GLP 共同负责刺激胰岛 β 细胞分泌胰岛素,并促进 β 细胞的增殖与存活。近期研究显示GIP 在调控脂质平衡及肥胖发病机制中发挥重要作用。 | |||
T64553 | GLP-1(7-37) TFA salt | ||
The truncated glucagon-like peptides GLP-1(7-37) is naturally occurring peptide product of the preproglucagon gene that are synthesized primarily in the intestine and acts as incretin that are released from the intestine into the bloodstream in response to food and stimulate insulin secretion. GLP-1(7-37) produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in Sprague-Dawley Rats at a dosing rang of 0.5, ... |