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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76995 Sotatercept

Sotatercept (ACE-011) 是一种可溶性激活素受体 2A (ACVR2A) 型 IgGFc 融合蛋白。Sotatercept 结合了激活素和生长分化因子,试图恢复生长促进和生长抑制信号通路之间的平衡。Sotatercept 在肺动脉高压、贫血、骨质流失、红细胞生成、多发性骨髓瘤 (MM) 溶骨性病变中有潜在的应用。

化合物

Sotatercept
Cat.No: T76995
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00893 IgG2a Protein, Rat, Recombinant

Ig γ-2A chain C region,Ig gamma-2A chain C...

Rat HEK293 Cells
Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and C...

重组蛋白

IgG2a Protein, Rat, Recombinant
Cat.No: TMPJ-00893
Species: Rat
Expression System: HEK293 Cells
TargetMol Loading
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