Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00703 |
IL-17Rc Protein, Human, Recombinant (hFc)
IL-17 receptor C,IL-17RC... |
Human | HEK293 Cells |
IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer. | |||
TMPJ-00376 |
IL-17RD Protein, Human, Recombinant (hFc)
IL17Rhom,IL17RD... |
Human | HEK293 Cells |
Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. It may inhibit FGF-induced FGFR1 tyrosine phosphorylation, regulate the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK By similarity, and mediate JNK activation ... |