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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35389 |
Sarilumab (anti-IL-6Rα)
|
IL Receptor | Immunology/Inflammation |
Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体,与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。 | |||
T76722 |
Sarilumab
REGN-88,SAR-153191 |
IL Receptor | Immunology/Inflammation |
Sarilumab(SAR-153191) 是一种有效的白细胞介素-6 IL-6 受体拮抗剂,是人源免疫球蛋白 G1 单克隆抗体。 Sarilumab 抑制由 IL-6 介导的信号传导,可减少炎症。Sarilumab 可用于预防和治疗类风湿关节炎。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00864 |
IL-6R Protein, Human, Recombinant (His)
IL-6R-1,IL-6RA,... |
Human | HEK293 Cells |
IL-6R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0N0L5. | |||
TMPY-05278 |
IL-6R Protein, Human, Recombinant (hFc)
IL-6R-1,CD126,gp80,IL |
Human | HEK293 Cells |
IL-6R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is A0N0L5. | |||
TMPY-05640 |
IL-6R Protein, Human, Recombinant, Biotinylated
IL6RQ,IL-6R,IL<... |
Human | HEK293 Cells |
IL-6R Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 67.1 kDa and the accession number is A0N0L5. | |||
TMPY-06297 |
IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated
CD126,IL-6RA,IL... |
Human | HEK293 Cells |
IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.80 kDa and the accession number is A0N0L5. | |||
TMPK-00289 |
IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)
IL-6R subunit alpha,IL-6... |
Human | HEK293 Cells |
The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expresse... |