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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T67930L |
CWI1-2 HCL
|
Apoptosis | Apoptosis |
CWI1-2 HCL 是一种有效的 IGF2BP2 抑制剂,结合 IGF2BP2 并抑制其与 m6A 修饰的靶转录物的相互作用,可诱导细胞凋亡和分化,具有治疗白血病的作用。 | |||
T67930 |
CWI1-2
|
Apoptosis | Apoptosis |
CWI1-2 是一种有效的 IGF2BP2 抑制剂,通过结合 IGF2BP2 抑制其与 m6A 修饰的靶转录物的相互作用。CWI1-2 具有抗白血病活性,可诱导细胞凋亡 (apoptosis)和分化。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00345 |
IGF2BP-2 Protein, Human, Recombinant (His)
IGF-II mRNA-Binding Protein 2, |
Human | E. coli |
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replicat... | |||
TMPY-01762 |
IGF2BP-2 Protein, Human, Recombinant (His & GST)
insulin-like growth factor 2 mRNA binding ... |
Human | Baculovirus Insect Cells |
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa c... |