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5

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T111959 IFB-088 acetate

IFB-088 acetate 是一种苄基胍衍生物,可用于治疗与PPP1R15A 途径相关并与蛋白质错误折叠应激相关的疾病和癌症,如tau 病、突触核蛋白病、多谷氨酰胺和多丙氨酸疾病、白质营养不良、囊性纤维化、多发性硬化症、溶酶体储存障碍、淀粉样变性疾病、炎症、代谢障碍、心血管疾病、骨质疏松症、神经系统创伤等等。
T9174 Icerguastat

Sephin 1,lcerguastat,IFB-088

Phosphatase Metabolism
Icerguastat (IFB-088) 是一种缺乏 α2-肾上腺素能活性的 Guanabenz 衍生物,是一种磷酸酶调节亚单位 PPP1R15A (R15A)的选择性抑制剂。它能够抑制 eIF2α 去磷酸化,从而延长保护反应。它具有抗朊病毒作用。
T21824 Sephin1

NSC 65390,IFB-088

Phosphatase Metabolism
Sephin1 (IFB-088) 是 GADD34 (PPP1R15A) 的选择性抑制剂,这是一种应激诱导的蛋白磷酸酶 1 复合物调节亚基,可将 eIF2α 去磷酸化。
T30869 Chaetominine

NSC 746369,NSC-746369,NSC746369

Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.
T35590 Graphislactone A

Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.

化合物

IFB-088 acetate
Cat.No: T111959
Synonym:
Target:
Icerguastat
Cat.No: T9174
Synonym: Sephin 1,lcerguastat,IFB-088
Target: Phosphatase
Sephin1
Cat.No: T21824
Synonym: NSC 65390,IFB-088
Target: Phosphatase
Chaetominine
Cat.No: T30869
Synonym: NSC 746369,NSC-746369,NSC746369
Target:
Graphislactone A
Cat.No: T35590
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03467 IFN-beta Protein, Mouse, Recombinant

Ifb,IFN-β,interferon, beta 1, fibroblast,干扰素,IFNB,I...

Mouse HEK293 Cells
IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575.
TMPY-03145 IFN-beta Protein, Human, Recombinant

IFN-β,interferon, β1, fibroblast,IFNB,IFB,IFF,Inter...

Human CHO Cells
IFN-beta Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 20 kDa and the accession number is P01574.
TMPY-00831 IFN-beta Protein, Human, Recombinant (hFc)

IFNB,IFN-β,Interferon beta,interferon, beta 1, fibroblast,In...

Human HEK293 Cells
IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38.
TMPY-02456 IFN-beta Protein, Mouse, Recombinant (hFc)

Ifb,interferon, β1, fibroblast,IFN-β,干扰素,interferon...

Mouse HEK293 Cells
IFN-beta Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is P01575.
TMPY-03851 BPIFB1 Protein, Human, Recombinant (His)

LPLUNC1,BPI fold containing family B, member 1,C20orf114

Human HEK293 Cells
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cel...

重组蛋白

IFN-beta Protein, Mouse, Recombinant
Cat.No: TMPY-03467
Species: Mouse
Expression System: HEK293 Cells
IFN-beta Protein, Human, Recombinant
Cat.No: TMPY-03145
Species: Human
Expression System: CHO Cells
IFN-beta Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00831
Species: Human
Expression System: HEK293 Cells
IFN-beta Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02456
Species: Mouse
Expression System: HEK293 Cells
BPIFB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03851
Species: Human
Expression System: HEK293 Cells
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