Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39503 |
Hepatitis Virus C NS3 Protease Inhibitor 2
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Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by a Ki value of 41 nM. | |||
T4474 |
Asunaprevir
BMS-650032,阿那匹韦 |
HCV Protease; SARS-CoV | Microbiology/Virology; Proteases/Proteasome |
Asunaprevir (BMS-650032) 是一种有口服活性的 HCV NS3 蛋白酶抑制剂,IC50值为 0.2 nM-3.5 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。 | |||
T4547 |
Grazoprevir
MK-5172 |
HCV Protease; SARS-CoV | Microbiology/Virology; Proteases/Proteasome |
Grazoprevir (MK-5172) 是一种丙型肝炎病毒 NS3/4a 蛋白酶的选择性抑制剂,具有跨基因型和耐药变体的广泛活性,对 gt1b、gt1a、gt2a、gt2b 和 gt3a 的Ki 分别为 0.01 nM、0.01 nM、0.08 nM、0.15 nM 和 0.90 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。 | |||
T8675 |
Vaniprevir
|
Others | Others |
Vaniprevir is a macrocyclic hepatitis C virus NS3/4a protease inhibitor and is active against both the genotype 1 and genotype 2 NS3/4a protease enzymes. vaniprevir has good plasma exposure and excellent liver exposure in multiple species. |