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Search Results for " hp1 "

Targets Recommended: Mitochondrial Metabolism

3

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9777	THP104c	Mitochondrial Metabolism	Metabolism
	THP104c 是有效的线粒体分裂抑制剂。
T61329	HP1142
	HP1142 is a highly effective and specific inhibitor targeting the FLT3 receptor tyrosine kinase, with a particular affinity for its mutant variant FLT3/ITD. It exhibits a benzoimidazole scaffold-based structure, making it a promising compound for investigating and studying the FLT3/ITD mutation in the context of leukemia research [1].
T61758	HP1328
	HP1328 is a highly effective inhibitor of FLT3 receptor tyrosine kinase with a specific focus on FLT3/ITD mutation. It belongs to the benzoimidazole scaffold-based compound family. Significantly reducing the leukemia burden, HP1328 effectively extends the survival of mice afflicted with FLT3/ITD leukemia [1].

化合物

Cat.No: T9777

Target: Mitochondrial Metabolism

Cat.No: T61329

Cat.No: T61758

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05431	TFF1 Protein, Human, Recombinant (His) trefoil factor 1,HP1.A,HP	Human	HEK293 Cells
	TFF1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.1 kDa and the accession number is P04155.
TMPK-00007	TFF1 Protein, Human, Recombinant (hFc) Polypeptide P1.A,Trefoil factor 1,Bcei,	Human	HEK293 Cells
	Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Human, Recombinant (hFc) is e...
TMPH-02503	DEFA1 Protein, Mouse, Recombinant (GST & His) HP-1,HNP-1,Defensin, alpha 1<...	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477.
TMPK-00941	TFF1 Protein, Mouse, Recombinant (hFc) HP1.A,D21S21,TFF1	Mouse	HEK293 Cells
	Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Mouse, Recombinant (hFc) is e...
TMPH-01772	DEFA1 Protein, Human, Recombinant (GST) MRS,HP1,HP-1,DEFA1	Human	E. coli
	Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665.
TMPH-01088	CBX5 Protein, Human, Recombinant (His & Myc) HP1 alpha,CBX5,Heterochromatin protein	Human	E. coli
	Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. CBX5 Protein...
TMPY-01657	SUV420H2 Protein, Human, Recombinant (His & GST) suppressor of variegation 4-20 homolog 2 (Drosophila),KMT5C	Human	E. coli
	Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-lysine methyltransferase family and Suvar4-2 subfamily. SUV42H2 is a histone methyltransferase that specifically trimethylates 'Lys-2' of histone H4. H4 'Lys-2' trimethylation represents a specific tag for epigenetic transcriptional repression. SUV42H2 mainly functions in pericentr...
TMPH-02274	JAK2 Protein, Human, Recombinant (His)	Human	E. coli
	Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int...

重组蛋白

TFF1 Protein, Human, Recombinant (His)

Cat.No: TMPY-05431

Species: Human

Expression System: HEK293 Cells

TFF1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00007

Species: Human

Expression System: HEK293 Cells

DEFA1 Protein, Mouse, Recombinant (GST & His)

Cat.No: TMPH-02503

Species: Mouse

Expression System: E. coli

TFF1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00941

Species: Mouse

Expression System: HEK293 Cells

DEFA1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01772

Species: Human

Expression System: E. coli

CBX5 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01088

Species: Human

Expression System: E. coli

SUV420H2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01657

Species: Human

Expression System: E. coli

JAK2 Protein, Human, Recombinant (His)

Cat.No: TMPH-02274

Species: Human

Expression System: E. coli

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