Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00817 |
Granzyme B/GZMB Protein, Human, Recombinant (His)
CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,granzyme B (g... |
Human | HEK293 Cells |
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G... | |||
TMPH-03487 |
DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His)
hnsA,hns,Histone-like protein HLP-II,DNA-binding pr... |
Serratia marcescens | E. coli |
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome. As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes. A subset of genes are repressed by H-NS in association with other proteins. DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His) is expre... | |||
TMPY-05321 |
CYP3A4 Protein, Human, Recombinant (His)
P450C3,P450PCN1,CYPIIIA4,CP34,cytochrome P450 family 3 subfa... |
Human | E. coli |
CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants. Human cytochrome P450 3A4 (CYP3A4) is an important drug metabolizing enzyme involved in a number of drug-drug and food-drug interactions. Systemic inflammation has been linked to suppressed CYP3A4 activity. | |||
TMPH-00616 |
DNA-binding protein H-NS Protein, E. coli, Recombinant (His)
hns,DNA-binding protein H-NS,Protein B1,Protein H1,Heat-stab... |
E. coli | E. coli |
A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstream and downstream of initiating RNA polymerase, trapping it in a loop and preventing transcription. Binds to hundreds of sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Many of these loci were horizontally transfe... | |||
TMPY-03506 |
VILIP1 Protein, Human, Recombinant
visinin-like 1,VILIP-1,VILIP,HUVISL1,HLP3,HPCAL3 |
Human | E. coli |
VILIP-1, also known as VSNL1, is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. VILIP-1 gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. Alternatively spliced transcript variants have been observed, but their full-length nature has not been... | |||
TMPY-02832 |
SHH Protein, Human, Recombinant (aa 198-462, His)
SMMCI,HLP3,HHG1,TPTPS,HPE3,MCOPCB5,TPT,Sonic hedgeh... |
Human | HEK293 Cells |
SHH Protein, Human, Recombinant (aa 198-462, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is Q15465. | |||
TMPY-02905 |
SHH Protein, Human, Recombinant (aa 1-197, His)
HHG1,MCOPCB5,SMMCI,Sonic hedgehog,TPTPS,HPE3,HLP3,T... |
Human | HEK293 Cells |
SHH Protein, Human, Recombinant (aa 1-197, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q15465. | |||
TMPJ-01048 |
VSNL1 Protein, Human, Recombinant (His)
VISL1,Visinin-Like Protein 1,Hippocalcin-Like Protein 3,... |
Human | E. coli |
Visinin-Like Protein 1 (VILIP) is a a member of the Visinin/Recoverin subfamily of neuronal calcium sensor proteins. VILIP is strongly expressed in the Granule Cells of the Cerebellum where it associates with membranes in a Calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of Adenylyl Cyclase. It has been shown that VILIP regulates the inhibition of rhodopsin phosphorylation in a Calcium-depende... | |||
TMPJ-00945 |
HPCAL1 Protein, Human, Recombinant (His)
Hippocalcin-Like Protein 1,HLP2,HPCAL1,VILIP-3,Calc... |
Human | E. coli |
Hippocalcin-Like Protein 1 (HPCAL1) is a neuron-specific calcium-binding member of the recoverin family which found in the retina and brain. HPCAL1 contains four EF-hand domains and it is highly similar to human hippocalcin protein. HPCAL1 is involved in the calcium-dependent regulation of rhodopsin phosphorylation. In addition, it may be of relevance for neuronal signalling in the central nervous system. |