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Cat. No. Product Name Species Expression System
TMPY-04930 Notch 2 Protein, Human, Recombinant (His)

AGS2,HJCYS,hN2,notch 2

Human Baculovirus Insect Cells
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. Hajdu Cheney Syndrome (HCS) is a rare disease associated with mutations of NOTCH2 that lead to the translation of a truncated, presumably stable, NOTCH2 protein. NOTCH2 is down-regulated in colon cancer, and reduced express...
TMPK-00466 Notch 2 Protein, Human, Recombinant (His & Avi), Biotinylated

NOTCH2,N2,N2ECD,Notch-2,HJCYS,AGS2

Human HEK293 Cells
Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch-2 is lethal, showing that not all functions overlap.Notch-2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intrac...
TMPK-00465 Notch 2 Protein, Human, Recombinant (His & Avi)

N2,Notch-2,HJCYS,AGS2,NOTCH2,N2ECD

Human HEK293 Cells
Human Notch 2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch 2 is lethal, showing that not all functions overlap.Notch 2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intrac...

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Notch 2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04930
Species: Human
Expression System: Baculovirus Insect Cells
Notch 2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00466
Species: Human
Expression System: HEK293 Cells
Notch 2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00465
Species: Human
Expression System: HEK293 Cells
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