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Cat. No. Product Name Target Signaling Pathways
T6420 BMS-707035

N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺

HIV Protease Microbiology/Virology; Proteases/Proteasome
BMS707035是一种 HIV-1 整合酶抑制剂,IC50为15 nM。
T15483 LEDGIN6

HIV-1 integrase inhibitor 2

Others Others
HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
T72162 HIV-1 integrase inhibitor 10

HIV-1integrase inhibitor 10 是一种 HIV-1变构整合酶抑制剂 (ALLINI),具有口服活性。HIV-1integrase inhibitor 10 可抑制 NLRepRluc 病毒在 MT-2 细胞中的生长,其 EC50值为 3-5 nM。HIV-1integrase inhibitor 10 可用于人类免疫缺陷病毒-1 (HIV-1) 的研究。
T36794 Dolutegravir O-β-D-Glucuronide

Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed from dolutegravir primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1in vivobut is also metabolized by UGT1A9 in human liver and kidney microsomes and UGT1A3 in human intestinal microsomes.2,1 1.Liu, S.N., Lu, J.B., Watson, C.J.W., et al.Mechanistic assessment of extrahepatic contributions to glucuronidation of integrase strand transfer inhibitorsDrug Metab. Dispos.47(5)535-544...

化合物

BMS-707035
Cat.No: T6420
Synonym: N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺
Target: HIV Protease
LEDGIN6
Cat.No: T15483
Synonym: HIV-1 integrase inhibitor 2
Target: Others
HIV-1 integrase inhibitor 10
Cat.No: T72162
Synonym:
Target:
Dolutegravir O-β-D-Glucuronide
Cat.No: T36794
Synonym:
Target:
TargetMol Loading
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