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Cat. No.	Product Name	Target	Signaling Pathways
T61844	HIV-1 inhibitor-9
	HIV-1 inhibitor-9 exhibits potent inhibition activity at low nanomolar concentrations against both the wild-type (WT) HIV-1 strain and multiple strains that have developed resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs).
T62156	HIV-1 integrase inhibitor 9
	HIV-1 integrase inhibitor 9 (compound 8a) 是一种 HIV-1 RNase H 的有效抑制剂 (IC50: 12.3 μM)，具有抗病毒作用。
T74211	HIV-1 inhibitor-12
	HIV-1inhibitor-12 是有效的 HIV-1抑制剂。HIV-1inhibitor-12 抑制 HIV-1衣壳蛋白聚合，IC50为 9 nM。
T79974	HIV-IN-8
	HIV-IN-8（Compound 9）为抗HIV药物，通过抑制HIV复制发挥作用，其半抑制浓度（EC50）为13 μg/mL。
T61797	HIV-1 inhibitor-15
	HIV-1 inhibitor-15 (compound 9d) is a potent and broad-spectrum inhibitor targeting HIV-1. It exhibits inhibitory activity against HIV-1 WT, L100I, K103N, Y181C, and E138K with respective EC50 values of 1.7 nM, 4 nM, 2 nM, 6 nM, and 9 nM. In addition to its high efficacy, HIV-1 inhibitor-15 possesses favorable solubility, safety profiles, and oral bioavailability [1].
T82194	HIV-IN-9
	HIV-IN-9 (Compound 2b)为一种HIV抑制剂，IC50值为6.65 μg/mL，对HIV-RT展现出高度结合亲和力。此外，HIV-IN-9亦能抑制CYP3A4、CYP1A2、CYP2C1和CYP2D6等多种酶。
T79295	HIV-1 protease-IN-9	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1protease-IN-9 (compound 5b)为HIV-1蛋白酶抑制剂，具有0.028 nM的Ki值和66.8 nM的IC50，表现出显著的抗病毒活性。
T35762	MC1742
	MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 It is selective for class I and class IIb over class IIa HDACs (IC50s = >50 μM for HDAC4, -5, -7, and -9). MC1742 reduces proliferation of HOS, MG-63, RD, A204, SK-ES-1, and A673 sarcoma cancer stem cells (CSCs). It increases levels of acetylated histone H3 and acetylated tubulin...

化合物

HIV-1 inhibitor-9

Cat.No: T61844

HIV-1 integrase inhibitor 9

Cat.No: T62156

HIV-1 inhibitor-12

Cat.No: T74211

Cat.No: T79974

HIV-1 inhibitor-15

Cat.No: T61797

Cat.No: T82194

HIV-1 protease-IN-9

Cat.No: T79295

Target: HIV Protease

Cat.No: T35762

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